Evidence map›Paper›PMID 40824656›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025

Mechanism of Injury Affects the Incidence and Time to Recovery of Nerve Injuries Associated With Humeral Shaft Fractures.

Margaret A Sinkler, Andy Kuo, Margaret Wang, John T Strony, Luc M Fortier, Kirsten Boes, George Ochenjele

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Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Margaret A SinklerFrom the Department of Orthopaedics (Dr. Sinkler, Dr. Strony, Dr. Fortier, Ms. Boes, and Dr. Ochenjele), University Hospitals Cleveland Medical Center, Cleveland, OH, and the Case Western Reserve University School of Medicine (Dr. Kuo and Dr. Wang), Cleveland, OH.ORCID 0000-0002-4409-1472
Andy Kuo
Margaret Wang
John T Strony
Luc M Fortier
Kirsten Boes
George Ochenjele

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to determine the incidence of pre- and postoperative nerve injuries associated with humeral shaft fractures.

methodsThree hundred eight humeral shaft fractures (Orthopaedic Trauma Association/Arbeitsgemeinschaft fur Osteosynthesefragen 12) underwent surgical treatment from 2009 to 2020 were reviewed. Nerve injury was identified by motor or sensory deficit. Patients were grouped by mechanism. Each cohort was evaluated for rate of nerve injury and exploration, onset of nerve recovery, and predictors of nerve injury.

resultsTwenty-four sustained gunshot wounds (GSWs), 73 high-energy injury mechanisms, and 211 low-energy injury mechanisms. Fifty-six preoperative and 14 postoperative nerve injuries were identified. Eight patients (33%) in the GSW cohort, 22(31%) with high-energy mechanisms, and 26 (13%) with low-energy mechanisms had a preoperative nerve injury (P < 0.001). One patient (4%) in the GSW cohort, 0 with high-energy mechanisms, and 13 (7%) with low-energy mechanisms had a postoperative nerve injury (P = 0.24). Preoperative nerve injuries from GSWs and high-energy mechanisms required more time for nerve recovery (6.8 vs. 5.2 vs. 4.0 months). Regression analysis showed that GSW (odds ratio = 4.79, P = 0.038, confidence interval = 1.79 to 15.87) and high-energy mechanisms (odds ratio = 2.34, P = 0.049, confidence interval = 1.004 to 5.784) were associated with preoperative nerve injury.

conclusionsGSWs and high-energy mechanisms have higher incidence of nerve injury associated with humeral shaft fractures and may require more time to recover.

Indexed as

Humeral FracturesPeripheral Nerve InjuriesPostoperative ComplicationsAdolescentAdultAgedFemaleHumansIncidenceMaleMiddle AgedRecovery of FunctionRetrospective StudiesTime FactorsWounds, GunshotYoung Adult

Identifiers

PMID40824656
PMCPMC12363442

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