Evidence map›Paper›PMID 40824585›Full record

ArticleClinical journal of gastroenterology2026

Pancreatic ductal adenocarcinoma originating from focal pancreatic parenchymal atrophy demonstrated by transabdominal ultrasonography.

Shogo Sakata, Takeshi Hisa, Yui Ito, Shigeru Nishiyama, Akiharu Kudo, Takahiro Yamada, Shozo Osera, Hideki Fukushima, Ryoga Hamura, Satoshi Shiozawa

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In one paragraph

Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shogo SakataDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan. sakata3815@gmail.com.ORCID http://orcid.org/0009-0002-8726-6807
Takeshi HisaDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan. hisa.takeshi@sakuhp.or.jp.ORCID http://orcid.org/0000-0002-8220-7595
Yui ItoDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Shigeru NishiyamaDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Akiharu KudoDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Takahiro YamadaDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Shozo OseraDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Hideki FukushimaDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Ryoga HamuraDepartment of Digestive Surgery, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Satoshi ShiozawaDepartment of Clinical Pathology, Saku Central Hospital Advanced Care Center, Nagano, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this report, we present an 80-year-old man referred for evaluation of a pancreatic mass detected by transabdominal ultrasonography during health screening. Additional examinations revealed severe, long-segment focal atrophy from the pancreatic head to the body, appearing as a cord-like hypoechoic lesion on transabdominal and endoscopic ultrasonography. Although cytological examination of pancreatic juice was recommended, the patient opted for a follow-up. Three years later, a hypoechoic mass with upstream main pancreatic duct dilatation developed in the atrophic region. Cytological examination of pancreatic juice revealed adenocarcinoma, and pancreaticoduodenectomy was performed. Histopathology revealed Stage IIB invasive ductal carcinoma and carcinoma in situ within the atrophic region. Retrospective review showed that focal atrophy was present on transabdominal ultrasonography 11 years before the invasive carcinoma mass appeared, progressing without main pancreatic duct dilatation until its development. During follow-up of focal atrophy, early diagnosis of carcinoma in situ or microinvasive carcinoma before main pancreatic duct dilatation is crucial. The present case suggests that severe, long-segment focal pancreatic parenchymal atrophy can be detected by transabdominal ultrasonography and that carcinoma in situ within the focal pancreatic parenchymal atrophy may progress to invasive carcinoma.

Indexed as

Carcinoma, Pancreatic DuctalPancreasPancreatic NeoplasmsAged, 80 and overAtrophyHumansMaleUltrasonographyCarcinoma in situEarly-stage pancreatic cancerEndoscopic ultrasoundHigh-grade pancreatic intraepithelial neoplasiaSerial pancreatic juice aspiration cytological examination

Identifiers

PMID40824585

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.