Evidence map›Paper›PMID 40824320›Full record

ArticleWorld journal of urology2025

Waiting for HoLEP-outcomes when complications arise in the preoperative period.

Clarissa Wong, Perry Xu, Meera Ganesh, Nabila Reem Khondakar, Luis Gago, Dimitri Speron, Kyle Tsai, Alyssa McDonald, Allaa Fadl-Alla, Nicholas Dean and 1 more

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Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Clarissa WongDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA. clarissa.wong@northwestern.edu.
Perry XuDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Meera GaneshDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Nabila Reem KhondakarDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Luis GagoDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Dimitri SperonDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Kyle TsaiDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Alyssa McDonaldDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Allaa Fadl-AllaDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Nicholas DeanDivision of Urology, University of Alberta, Edmonton, AB, Canada.
Amy KrambeckDepartment of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgery for benign prostatic hyperplasia (BPH), including holmium laser enucleation of the prostate (HoLEP), is often considered to be elective, leading to many patients waiting for intervention. Wait times for HoLEP can vary on many factors, but the incidence and impact of complications in this preoperative waiting period are unknown. We sought to uncover the outcomes of HoLEP in patients who experienced a complication while waiting for surgery.

methodsWe performed a retrospective review of a prospectively maintained database of patients who underwent HoLEP at a high-volume center between January 2021 and August 2023. Date of surgical case request placement, date of complication occurrence, and date of HoLEP were recorded. Preoperative, intraoperative, and postoperative characteristics were collected and analyzed. Statistical analysis was performed with SPSS software with p < 0.05 denoting significance.

resultsWe identified 918 patients in the database in this timeframe, with 74 experiencing a complication while waiting for HoLEP. Mean preoperative prostate volume was 122.7 ml. Complications included 8 cardiac and 37 urologic events. Complications were associated with a 31.2-day increase in wait time. Patients with cardiac complications waited 113.5 days (p = 0.013). Patients who had a complication while waiting were more likely to be on benign prostatic hyperplasia (BPH) medications, be catheter dependent, and have urinary tract infections (UTI) within 6 months of surgery. The 90-day postoperative complication rate was 31.5% in the complication group and 20.4% in the non-complication group. Patients who experienced a wait time complication were also more likely to have prolonged postoperative catheter duration and increased emergency room visits.

conclusionPatients with history of UTI and catheter dependence are more likely to experience a complication while waiting for HoLEP. Having a wait time complication can significantly delay surgery date by up to 30 days, and patients experiencing complication preoperatively are more likely to experience further complications postoperatively. Efforts are needed to expedite and improve access to necessary BPH procedures.

Indexed as

Lasers, Solid-StateLaser TherapyPostoperative ComplicationsProstatectomyProstatic HyperplasiaAgedHumansMaleMiddle AgedPreoperative PeriodRetrospective StudiesTime FactorsTreatment OutcomeBenign prostatic hyperplasia (BPH)Holmium laser enucleation of the prostate (HoLEP)Preoperative complicationsSurgical wait times

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.