Evidence map›Paper›PMID 40824260›Full record

ArticleTranslational vision science & technology2025

Enhancing the Readability of Online Pediatric Cataract Education Materials: A Comparative Study of Large Language Models.

Xinyi Qiu, Chaokun Luo, Qingruo Zhang, Ka Yi Chung, Weirong Chen, Hui Chen

Abstract readComparative Study
In one paragraph

Article in Translational vision science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinyi QiuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Chaokun LuoState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Qingruo ZhangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Ka Yi ChungState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Weirong ChenState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Hui ChenState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study was to assess large language models (LLMs) for enhancing the readability of online patient education materials (PEMs) on pediatric cataracts through multilingual adaptation, content retrieval, and prompt engineering. Methods: This study included 103 PEMs presented in different languages and retrieved from diverse resources. Three LLMs (ChatGPT-4o, Gemini 2.0, and DeepSeek-R1) were used for content improvement. Readability was assessed for both the original and converted PEMs with multiple formulas. Different prompt engineering strategies for LLMs were also tested in this study. Results: The PEMs directly generated by LLMs exceeded a 10th grade reading level. Compared to a traditional Google search, LLMs' web browsing feature provided online PEMs with better characteristics and a higher reading level. Original PEMs from Google showed significantly improved readability after LLM conversion, with DeepSeek-R1 achieving the greatest reduction in reading level from 10.59 ± 2.20 to 7.01 ± 0.91 (P < 0.001). Prompt engineering also showed statistically significant results in their effects on LLM conversion, and Zero-shot-Cot (APE) successfully achieving target readability below the sixth grade reading level. Besides, the LLMs' simplified Chinese conversion, as well as the LLMs conversion of other original Chinese PEMs, both showed that they meet the recommended standards for reading levels in multiple dimensions. Conclusions: LLMs can significantly enhance the readability of multilingual online PEMs on pediatric cataract. Combining it with web browsing and prompt engineering can further optimize outcomes and advance patient education. Translational Relevance: This study links LLMs with patient education and demonstrates their potential to significantly improve the readability of online PEMs.

Indexed as

CataractCataract ExtractionComprehensionLanguagePatient Education as TopicChildHumansInternetLarge Language ModelsReading

Identifiers

PMID40824260
PMCPMC12366858

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.