Evidence map›Paper›PMID 40824093›Full record

ArticleJournal of virology2025

Interaction of West Nile virus NS5 with orthoflavivirus SLA RNAs and their effects on viral replication and inhibition.

Mandi A Feinberg, My T Le, Kassandra L Carpio, Ekaterina Knyazhanskaya, Alan D T Barrett, Kyung H Choi

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mandi A Feinberg *Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA.
My T Le *Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana, USA.
Kassandra L Carpio *Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA.
Ekaterina Knyazhanskaya *Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0001-6161-4223
Alan D T BarrettDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Kyung H ChoiDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0003-0865-1265

Funding

Virology CoreU19AI171413 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SARKO, CHRISTOPHER · 2022 to 2023
$75.0M
X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Vivian Stojanoff · 2019 to 2026
$38.6M
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Gregory L Hura · 2017 to 2026
$28.6M
HOUSTON AREA MOLECULAR BIOPHYSICS TRAINING PROGRAMT32GM008280 · NIGMS · RICE UNIVERSITY · PI WENSEL, THEODORE G · 1988 to 2023
$8.0M
MECHANISM OF RNA SYNTHESIS BY DENGUE VIRUS NS5R01AI087856 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kyung H Choi · 2011 to 2026
$5.5M
DNA helicases and associated factors in genome stabilityR35GM133437 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BOCHMAN, MATTHEW LINNE · 2019 to 2023
$2.4M
A Simultaneous SAXS/WAXS Detector System for Solving Biological StructuresS10OD012331 · OD · STATE UNIVERSITY NEW YORK STONY BROOK · PI ALLAIRE, MARC · 2012 to 2012
$1.1M
NIAID NIH HHS R01 AI087856NIAID NIH HHS U19 AI171413NIGMS NIH HHS P30 GM124169NIGMS NIH HHS P30 GM133893NIGMS NIH HHS R35 GM133437NIGMS NIH HHS T32 GM008280NIH HHS S10 OD012331
6 · The paper itself

Abstract

West Nile virus (WNV) is a single-stranded, positive-sense RNA virus in the

Indexed as

RNA, ViralViral Nonstructural ProteinsVirus ReplicationWest Nile virus5' Untranslated RegionsAnimalsCell LineDengue VirusEncephalitis Virus, JapaneseGenome, ViralHumansNucleic Acid ConformationZika Virus5' Untranslated RegionsNS5 protein, flavivirusRNA, ViralViral Nonstructural ProteinsinfectioninhibitionNS5 polymeraseorthoflavivirusreplicationRNA promoterstem-loop AWest Nile virus

Identifiers

PMID40824093
PMCPMC12455937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.