Evidence map›Paper›PMID 40824060›Full record

ArticlemBio2025

A manganese-sparing response balances competing cellular demands to enable

Riley A McFarlane, Jana N Radin, Rafał Mazgaj, Kevin J Waldron, David Lalaouna, Thomas E Kehl-Fie

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Riley A McFarlaneDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Jana N RadinDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Rafał MazgajInstitute of Biochemistry and Biophysics Polish Academy of Sciences, Warsaw, Poland.
Kevin J WaldronInstitute of Biochemistry and Biophysics Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0002-5577-7357
David LalaounaUniversité de Strasbourg, CNRS, Architecture et Réactivité de l'ARN, UPR9002, Strasbourg, France.ORCID 0000-0002-0347-5816
Thomas E Kehl-FieDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0001-8234-1113

Funding

Calprotectin and Antibiotic Activities at the Infection InterfaceR01AI179695 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian Patrick Conlon, Thomas Everett Kehl-Fie · 2024 to 2026
$2.3M
Agence Nationale de la Recherche ANR-20-CE12-0021Narodowe Centrum Nauki 2021/42/A/NZ1/00214NIAID NIH HHS R01 AI179695NIH HHS AI179695University of Iowa P3 Strategic Initiative High Impact Hiring Initiative (HIHI): A Program to Strategically Recruit and Retain Talented Faculty
6 · The paper itself

Abstract

Responding to stress is critical to the survival of life, especially for microbes that have a limited ability to manipulate their environment. During infection, IMPORTANCE: During infection, pathogens must utilize processes that impose conflicting cellular demands. This conflict is exemplified by the need of

Indexed as

ManganeseStaphylococcal InfectionsStaphylococcus aureusAnimalsGene Expression Regulation, BacterialHost-Pathogen InteractionsHumansMiceOxidative StressRNA, BacterialRNA, Small UntranslatedSuperoxide DismutaseVirulenceManganeseRNA, BacterialRNA, Small UntranslatedSuperoxide Dismutasemanganesemetal limitationoxidative stressRsaCsmall RNAStaphylococcus aureussuperoxide dismutase

Identifiers

PMID40824060
PMCPMC12421985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.