Conservation and evolution of the programmed ribosomal frameshift in

Cassidy R Prince, Isabella N Lin, Heather A Feaga

Abstract read

In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Compensatory evolution facilitates loss of prfB autoregulation in Pseudomonas fluorescens SBW25.Molecular biology and evolution · 2026
Article

4 · The record

Corrections and comments

Update of
Conservation and evolution of the programmed ribosomal frameshift in2025

5 · Who and what money

Authors and funding

3 authors.

Cassidy R PrinceDepartment of Microbiology, Cornell University, Ithaca, New York, USA.ORCID 0000-0003-2740-522X

Isabella N LinDepartment of Microbiology, Cornell University, Ithaca, New York, USA.ORCID 0009-0003-9491-1971

Heather A FeagaDepartment of Microbiology, Cornell University, Ithaca, New York, USA.ORCID 0009-0007-3190-5135

Funding

Ribosome Quality Control Mechanisms in Gram-Positive BacteriaR35GM147049 · NIGMS · CORNELL UNIVERSITY · PI Heather Feaga · 2022 to 2026

$1.9M

NIGMS NIH HHS R35 GM147049NIGMS NIH HHS R35GM147049

6 · The paper itself

Abstract

When the ribosome reaches a stop codon, translation is terminated by a release factor. Bacteria encode two release factors, RF1 and RF2. In many bacteria, the gene encoding RF2 (

Indexed as

BacteriaEscherichia coli ProteinsEvolution, MolecularFrameshifting, RibosomalPeptide Termination FactorsCodon, TerminatorConserved SequenceEscherichia coliGenome, BacterialCodon, TerminatorEscherichia coli ProteinsPeptide Termination FactorsprfB protein, E coliActinomycetotaevolutionprfBprogrammed ribosomal frameshiftingRF2ribosometranslation termination

Identifiers

PMID40824027

DOI10.1128/mbio.01055-25

PMCPMC12421855

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.