Evidence map›Paper›PMID 40823869›Full record

ArticleAntimicrobial agents and chemotherapy2025

Synergistic interaction between praziquantel and oxfendazole or fenbendazole in a murine cysticercosis model.

Palomares-Alonso Francisca, González-Maciel Angélica, Reynoso-Robles Rafael, Castro Nelly, Pérez-Severiano Francisca, Sánchez-Mendoza Alicia, Jung-Cook Helgi, Bravo Guadalupe, López-Muñoz Francisco

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Palomares-Alonso FranciscaLaboratorio de Neuroinflamación, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México, Mexico.ORCID 0009-0002-6929-8231
González-Maciel AngélicaLaboratorio de Morfología Celular y Tisular, Instituto Nacional de Pediatría, Ciudad de México, Mexico.ORCID 0000-0003-1909-9146
Reynoso-Robles RafaelLaboratorio de Morfología Celular y Tisular, Instituto Nacional de Pediatría, Ciudad de México, Mexico.
Castro NellyLaboratorio de Neurobioquímica y Conducta, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México, Mexico.ORCID 0000-0002-8746-8751
Pérez-Severiano FranciscaLaboratorio de Neurofarmacología molecular y nanotecnología, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México, Mexico.ORCID 0000-0002-2840-7991
Sánchez-Mendoza AliciaDepartamento de Farmacología, Instituto Nacional de Cardiología, Ciudad de México, Mexico.ORCID 0000-0002-3067-8344
Jung-Cook HelgiFacultad de Química, Departamento de Farmacia, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.ORCID 0000-0002-2032-4753
Bravo GuadalupeLaboratorio de Morfología Celular y Tisular, Instituto Nacional de Pediatría, Ciudad de México, Mexico.ORCID 0000-0002-2730-7761
López-Muñoz FranciscoDepartamento de Farmacobiología, Cinvestav-Sede Sur, Ciudad de México, Mexico.ORCID 0000-0002-5188-6038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up to date, the pharmacological treatment for active neurocysticercosis (NCC) includes only two drugs, praziquantel and albendazole; however, the clinical response is not always successful, due to its low bioavailability; therefore, new approaches are needed. The aim of the present study was to evaluate the pharmacological interaction between praziquantel (PZQ) and oxfendazole (OXF)

Indexed as

AnthelminticsBenzimidazolesCysticercosisFenbendazoleNeurocysticercosisPraziquantelAnimalsDisease Models, AnimalDrug SynergismDrug Therapy, CombinationMiceTaeniaAnthelminticsBenzimidazolesFenbendazoleoxfendazolePraziquantelfenbendazolemurine cysticercosisoxfendazolepraziquantel and synergistic effect

Identifiers

PMID40823869
PMCPMC12486855

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.