Evidence map›Paper›PMID 40823867›Full record

ArticleAntimicrobial agents and chemotherapy2025

Synergistic activity of RSL3 and Pyrimethamine to inhibit the proliferation of

Vella Nikolova, Karen Linnemannstöns, Anastasiia Zahoruiko, Markus Ganter, Carsten G Lüder, Matthias Dobbelstein

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vella NikolovaDepartment of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0002-1334-3008
Karen LinnemannstönsDepartment of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, Göttingen, Germany.
Anastasiia ZahoruikoDepartment of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, Göttingen, Germany.
Markus GanterCenter for Infectious Diseases - Parasitology, Medical Faculty, Heidelberg University, Heidelberg, Germany.ORCID 0000-0003-0684-2260
Carsten G LüderInstitute of Medical Microbiology and Virology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0001-6228-6356
Matthias DobbelsteinDepartment of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0001-5052-3967

Funding

German Research Council SFB 1129
6 · The paper itself

Abstract

Malaria tropica, caused by

Indexed as

AntimalarialsPlasmodium falciparumPyrimethamineAnimalsDrug SynergismErythrocytesHumansLipid PeroxidationMalaria, FalciparumProguanilTetrahydrofolate DehydrogenaseTriazinesAntimalarialscycloguanilProguanilPyrimethamineTetrahydrofolate DehydrogenaseTriazinesCycloguanilferroptosismalariaPlasmodium falciparumPyrimethamineRSL3

Identifiers

PMID40823867
PMCPMC12486841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.