Evidence map›Paper›PMID 40823844›Full record

ArticlemBio2025

Antibiotics and phages drive region-specific diversity of OmpK36 in

Guilhem Royer, Raphaël Laurenceau, Nicolas Cabanel, Benjamin Bardiaux, Karol Melissa Cerdas-Mejías, David Bikard, Isabelle Rosinski-Chupin, Philippe Glaser

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bacteriophage-induced outer membrane protein remodelling drives the phenotypic switching and antibiotic re-sensitization in Klebsiella pneumoniae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guilhem RoyerInstitut Pasteur, Université Paris Cité, CNRS UMR6047, Ecology and Evolution of Antibiotic Resistance Unit, Paris, France.ORCID 0000-0001-9092-8336
Raphaël LaurenceauInstitut Pasteur, Université de Paris Cité, CNRS UMR3525, Synthetic Biology Unit, Paris, France.
Nicolas CabanelInstitut Pasteur, Université Paris Cité, CNRS UMR6047, Ecology and Evolution of Antibiotic Resistance Unit, Paris, France.
Benjamin BardiauxInstitut Pasteur, Université Paris Cité, CNRS UMR3528, Structural Bioinformatics Unit, Paris, France.ORCID 0000-0003-4014-9195
Karol Melissa Cerdas-MejíasInstitut Pasteur, Université de Paris Cité, CNRS UMR3525, Synthetic Biology Unit, Paris, France.
David BikardInstitut Pasteur, Université de Paris Cité, CNRS UMR3525, Synthetic Biology Unit, Paris, France.
Isabelle Rosinski-ChupinInstitut Pasteur, Université Paris Cité, CNRS UMR6047, Ecology and Evolution of Antibiotic Resistance Unit, Paris, France.
Philippe GlaserInstitut Pasteur, Université Paris Cité, CNRS UMR6047, Ecology and Evolution of Antibiotic Resistance Unit, Paris, France.ORCID 0000-0003-4156-2782

Funding

Agence Nationale de la Recherche ANR-20-PAMR-0010)Institut Pasteur GROOT-22
6 · The paper itself

Abstract

The IMPORTANCE: Porins are outer membrane proteins involved in the passive diffusion into the periplasm of substrates such as nutrients. They are also a major route for antibiotics. Mutations in the main porins of

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBacteriophagesGenetic VariationKlebsiella pneumoniaePorinsDrug Resistance, BacterialGenome, BacterialMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial ProteinsOmpK36 protein, Klebsiella pneumoniaePorinsantibiotic resistancebacteriophagesgenome analysisOmpK36porins

Identifiers

PMID40823844
PMCPMC12421954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.