Evidence map›Paper›PMID 40823841›Full record

ArticlemBio2025

AP2X-1 is a negative regulator of

Li-Xiu Sun, Meng Wang, Tian-Yu Zhang, Hany M Elsheikha, Zhi-Wei Zhang, Xiao-Nan Zheng, Bao-Quan Fu, Xing-Quan Zhu, Guo-Hua Liu, Jin-Lei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Live Attenuated AP2X-1-DeficientAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li-Xiu SunState Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, People's Republic of China.
Meng WangState Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, People's Republic of China.
Tian-Yu ZhangState Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, People's Republic of China.
Hany M ElsheikhaSchool of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences, Sutton Bonington Campus, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0003-3303-930X
Zhi-Wei ZhangState Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, People's Republic of China.
Xiao-Nan ZhengLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Taiyuan, Shanxi, People's Republic of China.
Bao-Quan FuState Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, People's Republic of China.
Xing-Quan ZhuLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Taiyuan, Shanxi, People's Republic of China.ORCID 0000-0003-2530-4628
Guo-Hua LiuResearch Center for Parasites & Vectors, College of Veterinary Medicine, Hunan Agricultural University, Changsha, Hunan, People's Republic of China.ORCID 0000-0002-8434-899X
Jin-Lei WangState Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, People's Republic of China.ORCID 0000-0002-2373-9049

Funding

Chinese Academy of Agricultural Sciences CAAS-ASTIP-JBGS-20210801National Key Research and Development Program of China 2022YFD1800200National Natural Science Foundation of China 32172887National Natural Science Foundation of China 32422085Natural Science Foundation of Gansu Province 23JRRA1479Natural Science Foundation of Gansu Province 23JRRA553
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Life Cycle StagesProtozoan ProteinsToxoplasmaAnimalsGene Expression RegulationGene Knockout TechniquesHistone DeacetylasesMiceToxoplasmosisHistone DeacetylasesProtozoan ProteinsAP2X-1gene expressionHDAC3/MORC complexsexual developmentToxoplasma gondiitranscription

Identifiers

PMID40823841
PMCPMC12421964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.