Evidence map›Paper›PMID 40823824›Full record

ArticlemBio2025

The evolutionary replacement of restriction-modification by Ssp antiviral systems is associated with the distribution of prophages in the major clonal group of

Antonio Moreno-Rodríguez, Alejandro Rubio, Andrés Garzón, Younes Smani, Antonio J Pérez-Pulido

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bacterial immune systems.Antonie van Leeuwenhoek · 2026
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antonio Moreno-RodríguezAndalusian Centre for Developmental Biology (CABD, UPO-CSIC-JA), Seville, Spain.ORCID 0000-0002-4053-1426
Alejandro RubioAndalusian Centre for Developmental Biology (CABD, UPO-CSIC-JA), Seville, Spain.ORCID 0000-0002-6736-6141
Andrés GarzónAndalusian Centre for Developmental Biology (CABD, UPO-CSIC-JA), Seville, Spain.ORCID 0000-0003-4299-7198
Younes SmaniAndalusian Centre for Developmental Biology (CABD, UPO-CSIC-JA), Seville, Spain.ORCID 0000-0001-9302-8384
Antonio J Pérez-PulidoAndalusian Centre for Developmental Biology (CABD, UPO-CSIC-JA), Seville, Spain.ORCID 0000-0003-3343-2822

Funding

Agencia Estatal de Investigación CEX2020-001088-M-20-5Agencia Estatal de Investigación PID2023-150077OB-I00/AEI/10.13039/501100011033/ FEDER UEAgencia Estatal de Investigación PRE2022-104318
6 · The paper itself

Abstract

Bacteriophages kill almost half of the world's bacterial cells every day. In response, bacteria have developed anti-phage defense mechanisms that number in the dozens. Individual defense systems are gained and lost by genomes of the same species, depending on their fitness advantage. Thus, the combination of defense systems presented by the individual genomes may differ, and the collection of all of them is what is known as the pan-immune system of the species. Here, we have analyzed thousands of genomes of the bacterium

Indexed as

Acinetobacter baumanniiDNA Restriction-Modification EnzymesEvolution, MolecularProphagesGenome, BacterialHumansDNA Restriction-Modification EnzymesAcinetobacter baumanniianti-phage systemCRISPR-Casdefense systemrestriction-modificationSsp

Identifiers

PMID40823824
PMCPMC12421847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.