Evidence map›Paper›PMID 40823581›Full record

ArticleFrontiers in medicine2025

Inflammatory markers CRP and WBC as predictors of liver function impairment in multiple injury trauma patients: a repeated measures analysis.

Gang Wang, Cui Tang, Rui Wang, Chundao Xu, Tugang Shen, Gaokai Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gang Wang *School of Life and Health, Huzhou College, Huzhou, Zhejiang, China.
Cui Tang *Zhejiang Xinda Hospital, Huzhou, Zhejiang, China.
Rui WangSchool of Life and Health, Huzhou College, Huzhou, Zhejiang, China.
Chundao XuDepartment of Orthopaedics, South Taihu Hospital Affiliated to Huzhou College, Huzhou, Zhejiang, China.
Tugang ShenDepartment of Orthopaedics, South Taihu Hospital Affiliated to Huzhou College, Huzhou, Zhejiang, China.
Gaokai LiSchool of Life and Health, Huzhou College, Huzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To investigate the relationship between liver function indices (AST, ALT, GGT) and inflammatory markers (CRP, white blood cell count) in multiple injury patients at different time points post-trauma. Methods: We retrospectively analyzed 114 patients with multiple injuries admitted to a tertiary trauma center in Zhejiang Province (January 2023-December 2024). AST, ALT, GGT, CRP, white blood cell count, NLR, and LMR were measured at admission, 24 h, and 72 h post-admission. Age, drinking history, BMI, and gender were included as covariates. Statistical analyses employed both crude and adjusted GEE models with gender subgroup analysis. Results: Elevated CRP levels significantly correlated with increased AST (OR = 2.17, 95% CI: 1.14-4.12, Conclusion: CRP and white blood cell count significantly correlate with liver function changes in multiple injury patients, with marked gender-specific differences in these associations. These findings suggest the need for sex-specific monitoring strategies in trauma-related hepatic dysfunction.

Indexed as

gender differencegeneralized estimating equationinflammatory indexliver function indexmultiple trauma

Identifiers

PMID40823581
PMCPMC12354656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.