ArticleEClinicalMedicine2025
A simple VA-ECMO bundle in adult patients with cardiogenic shock: an analysis of ELSO registry.
Article in EClinicalMedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07351435 (The Caribbean Registry of Extracorporeal Membrane Oxygenation), which is not on this map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
Who cites it
3 citing papers in PubMed.
- Modifying a traditional femoral venoarterial extracorporeal membrane oxygenation cannulation strategy and circuit to improve distal limb hemodynamics.JTCVS open · 2026Article
- PD-1/TIGIT CD4⁺ T-Cell Signature for Risk Stratification of Post-Weaning Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients.Journal of inflammation research · 2026Article
- Venoarterial extracorporeal membrane oxygenation in adults with cardiogenic shock.Frontiers in cardiovascular medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The optimal management strategy for patients undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock (CS) remains uncertain. To evaluate the impact of "bundled" physiologic targets on outcomes in VA-ECMO patients. Methods: This retrospective cohort study analyzed data from the Extracorporeal Life Support Organization (ELSO) registry, including adult patients receiving VA-ECMO for CS between 2013 and 2022. Patients were grouped by whether they received the full set of bundle components within the first 24 h. The bundle included mean arterial pressure > 65 mmHg, PaO Findings: Of 7950 patients (mean age 56.5 ± 14.3 years), 2762 (34.7%) received the complete bundle. The bundle group had significantly higher rates of survival to hospital discharge (55.9% vs. 39.4%, Interpretation: Achieving the proposed physiologic bundle is associated with improved survival and a reduced risk of complications in VA-ECMO patients with CS. These findings provide evidence supporting the use of standardized care bundles in the management of VA-ECMO patients with CS. Funding: This work was supported by the Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support (No. ZYLX202111, to X Hou), Beijing Hospitals Authority "Ascent Plan" (No. FDL20190601, to X Hou), Young Elite Scientists Sponsorship Program by CAST (No. 2022QNRC001, to L Wang), National Natural Science Foundation of China (No. 82200433, to L Wang), and Beijing Hospitals Authority Youth Programme (No. QML20230602, to L Wang), National Natural Science Foundation of China (No. 82100408, to X Hao), Beijing Nova Program (No. 2022064, to C Li), Beijing Natural Science Foundation (No. 7244327, to C Li), and the National Key Research and Development Program of China (No. 2021YFC2701700 and 2021YFC2701703, to Z Du).
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