Evidence map›Paper›PMID 40823460›Full record

ArticleCureus2025

Clinical Impact of Neuropostural and Neuromuscular Optimization Protocols With Radio Electric Asymmetric Conveyer (REAC) Technology in Older Adults With Femoral Fractures: An Observational Study.

Bruna Lombardi, Margherita Imbrenda, Valtere Giovannini, Vania Fontani, Salvatore Rinaldi

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Bruna LombardiResearch Department, Rinaldi Fontani Foundation, Firenze, ITA.
Margherita ImbrendaPhysical and Rehabilitative Medicine Center, Azienda USL Toscana, Prato, ITA.
Valtere GiovanniniPhysical Medicine and Rehabilitation, Casa di Cura Villa Fiorita, Prato, ITA.
Vania FontaniResearch Department, Rinaldi Fontani Foundation, Florence, ITA.
Salvatore RinaldiResearch Department, Rinaldi Fontani Foundation, Florence, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFemoral fractures in the elderly often result in long-lasting disability. Standard rehabilitation may fail to address neurofunctional alterations such as functional dysmetria (FD), which limit optimal motor recovery. This study evaluates the clinical utility of Radio Electric Asymmetric Conveyer (REAC) neuromodulation protocols, Neuro Postural Optimization (NPO) and Neuro Muscular Optimization (NMO), as adjuncts to standard rehabilitation in elderly patients post femoral fracture surgery.

methodsThis observational study was conducted at Casa di Cura Villa Fiorita (59100, Prato, Italy), within a clinical-scientific collaboration program with the Rinaldi Fontani Institute. Fourteen elderly patients (mean age 81.7 years) received one NPO session, followed by 10 NMO sessions in conjunction with standard physiotherapy. A matched historical control group (n = 14) received only conventional therapy. Assessed parameters included the Barthel Index (BI), Visual Analogue Scale (VAS) for pain, FD presence, and hospital length of stay. Statistical analysis used paired/unpaired t-tests (p < 0.05).

resultsFD was completely resolved in all REAC-treated patients following the single NPO session. This neurobiological modulation likely restores subcortical and cerebellar network homeostasis, enabling symmetrical motor output. The NMO protocol supported neuromotor pattern optimization throughout recovery. Compared to controls, the REAC group achieved significantly greater improvements in BI (+47.1 vs. +38.1 points,

conclusionsThe integration of REAC NPO and NMO protocols into conventional rehabilitation enhanced motor symmetry, pain control, and recovery speed. These findings justify further randomized trials and suggest REAC neuromodulation as a valuable, non-invasive, and scalable strategy in orthopedic rehabilitation.

Indexed as

femoral fracturesfunctional dysmetriageriatric rehabilitationneurobiological modulationneuromuscular optimizationneuropostural optimizationnon-invasive neuromodulationpain reductionpostural symmetryreac technology

Identifiers

PMID40823460
PMCPMC12357592

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.