Evidence map›Paper›PMID 40823449›Full record

ArticleCureus2025

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Case Report Highlighting Diagnostic Challenges and the Role of Immunohistochemistry.

Thanh Thao Nguyen, Mitsuaki Yoshida, Vu Dung, Motona Kumagai, Sohsuke Yamada

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thanh Thao NguyenDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, JPN.
Mitsuaki YoshidaDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, JPN.
Vu DungDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, JPN.
Motona KumagaiDepartment of Pathology, Kanazawa Medical University Hospital, Ishikawa, JPN.
Sohsuke YamadaDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare, benign vascular lesion that poses significant diagnostic challenges owing to its nonspecific clinical and radiological features. We herein report the case of a 35-year-old male who presented with chronic left hypochondrial pain and was found to have a splenic mass with poor enhancement on computed tomography (CT) and an increased fluorodeoxyglucose uptake on positron emission tomography-CT. Total splenectomy was performed, and a histopathological examination revealed well-demarcated angiomatoid nodules with varying vascular channels, fibrosclerosis, and hemosiderin deposition. Immunohistochemistry revealed a characteristic tri-phenotypic vascular profile of CD34

Indexed as

immunohistochemistrysclerosing angiomatoid nodular transformationspleensplenectomyvascular tumors

Identifiers

PMID40823449
PMCPMC12350054

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.