ArticleJournal of inflammation research2025
Neutrophil-to-Albumin Ratio Predicts Stroke-Associated Pneumonia in Patients with Intracerebral Hemorrhage.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association of the neutrophil percentage-to-albumin ratio after endovascular treatment and 3-month clinical outcomes.Frontiers in neurologyTrial
- The neutrophil-to-albumin ratio is associated with in-hospital mortality in patients with cirrhosis and pneumonia: a multicenter retrospective cohort study.BMC infectious diseases · 2026Article
- The Neutrophil-to-Albumin Ratio (NAR) Reflects the Severity of the Post-CABG Inflammatory Response and Is Associated with a Pre-Existing Pro-Inflammatory Monocyte Profile.Life (Basel, Switzerland) · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aim: Pneumonia is a significant complication that negatively impacts outcomes in patients with intracerebral hemorrhage (ICH). Identifying reliable biomarkers for predicting such infections is crucial for timely intervention and improving patient management. This study aims to evaluate the predictive value of neutrophil-to-albumin Ratio (NAR)for pneumonia in patients undergoing surgical intervention for ICH. Methods: This was a retrospective multicenter cohort study conducted at four tertiary hospitals. A total of 8016 patients diagnosed with spontaneous intracerebral hemorrhage (ICH) between were included. The neutrophil-to-albumin ratio (NAR) was calculated within 24 hours of admission. Logistic regression models, receiver operating characteristic (ROC) curves, and reclassification metrics (C-index, IDI, cNRI) were used to evaluate the association between NAR and the risk of pneumonia. The primary outcome was pneumonia. Results: A total of 8016 ICH patients were included in this study. Among them, 3921 patients (48.9%) had pneumonia. There was an association between NAR levels and pneumonia (OR = 1.81, 95% CI: 1.69-1.94, p < 0.001). After adjustment, the results remained significant (adjusted OR = 1.62, 95% CI: 1.51-1.75, p < 0.001). Compared to patients in the Low Group (NAR ≤ 0.21), those in the High Group (NAR > 0.21) had a higher long-term mortality risk (OR = 2.95, 95% CI: 2.68-3.24, p < 0.001; adjusted OR = 1.99, 95% CI: 1.79-2.21, p < 0.001). Additionally, the predictive performance of NAR for pneumonia was also significant (area under the ROC curve [95% CI] 0.663 [0.651-0.675]; p < 0.001). Conclusion: Higher NAR is independently associated with pneumonia in patients with ICH. The early prediction of pneumonia using the simple biomarker NAR is feasible.
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