ArticleFrontiers in neurology2025
Decomposing door-to-needle time: insights into workflow delays and quality improvement in acute stroke care.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Real-World Comparison of Stroke Practitioner-Led and Neurohospitalist-Led Acute Ischemic Stroke Workflows.Healthcare (Basel, Switzerland) · 2026Article
- Understanding door-to-needle delays in acute ischemic stroke: a workflow-based analysis of emergency department care processes.BMC emergency medicine · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Timely administration of intravenous recombinant tissue plasminogen activator (rtPA) significantly improves outcomes in acute ischemic stroke (AIS). However, substantial variability in door-to-needle (DTN) time persists in real-world settings. This study aimed to deconstruct DTN time into distinct workflow intervals to identify key determinants of delay and inform targeted quality improvement. Methods: This retrospective study included 322 consecutive AIS patients treated with intravenous rtPA at Dongyang People's Hospital between May 2023 and April 2025. DTN time was divided into four intervals: door-to-order time (ODT), order-to-imaging completion time (OCT), imaging completion-to-consent time (ICT), and consent-to-needle time (CNT). Real-time data were collected through beacon-based tracking and a time-tracking application. Linear regression, correlation, and subgroup analyses were used to explore factors associated with each interval and overall DTN time. Results: Among all intervals, ICT showed the strongest correlation with DTN time ( Conclusion: Physician seniority, thrombolysis strategy, and MRI-negative status significantly influence DTN time. Segmenting DTN time enables precise identification of key delays across different workflow stages and may enhance the efficiency of acute stroke care.
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