Evidence map›Paper›PMID 40823203›Full record

ArticleInternational journal of mental health and addiction2024

Prevalence and Correlates of Depression and Bipolar Disorder Among Patients Maintained on Methadone and Buprenorphine in Ukraine.

Olga Morozova, Vira Dvoriak, Kostyantyn Dumchev, Eteri Machavariani, Daniel J Bromberg, Sergii Dvoriak, Frederick L Altice

Abstract read
In one paragraph

Article in International journal of mental health and addiction, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olga MorozovaDepartment of Public Health Sciences, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA.ORCID 0000-0001-7606-8413
Vira DvoriakUkrainian Institute On Public Health Policy, Kyiv, Ukraine.
Kostyantyn DumchevUkrainian Institute On Public Health Policy, Kyiv, Ukraine.
Eteri MachavarianiSection of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.
Daniel J BrombergCenter for Interdisciplinary Research On AIDS, Yale University, New Haven, CT, USA.
Sergii DvoriakUkrainian Institute On Public Health Policy, Kyiv, Ukraine.
Frederick L AlticeSection of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.

Funding

Integrating Treatment for Mental Disorders in Methadone Clinics in UkraineU01DA045384 · NIDA · UKRAINIAN INSTITUTE ON PUBLIC HEALTH POLICY · PI DVORIAK, SERGII · 2018 to 2020
$1.4M
Ukraine HIV Research Training Program/Aging SupplementD43TW012491 · FIC · SUNY DOWNSTATE MEDICAL CENTER · PI Jack A DeHovitz, Tetiana Kiriazova · 2023 to 2026
$1.0M
Integrating Treatment for Mental Disorders in Methadone Clinics in UkraineR01DA045384 · NIDA · UKRAINIAN INSTITUTE ON PUBLIC HEALTH POLICY · PI DVORIAK, SERGII · 2021 to 2022
$884k
FIC NIH HHS D43 TW012491NIDA NIH HHS R01 DA045384NIDA NIH HHS U01 DA045384
6 · The paper itself

Abstract

Psychiatric and substance use disorders frequently coexist and require co-management, yet little is known about the prevalence of psychiatric disorders among patients maintained on medications for opioid use disorder (MOUD) in Ukraine. We analyzed baseline data from a cluster-randomized trial of an integrated model of depression diagnosis and treatment among MOUD patients in Ukraine to determine prevalence and correlates of depression and bipolar disorder in this population. From a randomly selected sample of 1345 patients on MOUD at 12 sites in Ukraine, screening for moderate/severe depression (PHQ-9) and bipolar disorder (MDQ) yielded high prevalence of 50% (95% CI 42-58%) and 12% (95% CI 8-16%), respectively. Correlates of depression included recent drug injection, worse physical health, shorter duration on MOUD, higher methadone dosages, and stigma levels, being unmarried and having low trust in physicians. Bipolar disorder was correlated with alcohol use disorder and prior incarceration. The high burden of mental health disorders among patients prescribed MOUD in Ukraine calls for the urgent implementation of models to address co-occurring disorders, including those using integrated care strategies.

Indexed as

Eastern EuropeIntegrated careMedications for opioid use disorder (MOUD)Mental healthOpioid agonist treatment (OAT)Psychiatric disorders

Identifiers

PMID40823203
PMCPMC12356126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.