Evidence map›Paper›PMID 40823181›Full record

ArticleOpen medicine (Warsaw, Poland)2025

Uterine fibroid embolization: An analysis of clinical outcomes and impact on patients' quality of life.

Nicolò Ubaldi, Marcello Andrea Tipaldi, Andrea Giannini, Tullio Golia D'Augè, Donatella Caserta, Antonio Simone Laganà, Giacomo Grasso, Aleksejs Zolovkins, Edoardo Ronconi, Michele Rossi

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In one paragraph

Article in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicolò UbaldiDepartment of Surgical and Medical Sciences and Translational Medicine, Azienda Ospedaliera Sant'Andrea, Sapienza University of Rome, Rome, Italy.
Marcello Andrea TipaldiDepartment of Surgical and Medical Sciences and Translational Medicine, Azienda Ospedaliera Sant'Andrea, Sapienza University of Rome, Rome, Italy.
Andrea GianniniDepartment of Gynecological, Obstetrical and Urological Sciences, "Sapienza" University of Rome, Rome, Italy.
Tullio Golia D'AugèDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, 00161, Italy.
Donatella CasertaDepartment of Gynecological, Obstetrical and Urological Sciences, "Sapienza" University of Rome, Rome, Italy.
Antonio Simone LaganàUnit of Obstetrics and Gynecology, Paolo Giaccone Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127, Palermo, Italy.
Giacomo GrassoDepartment of Surgical and Medical Sciences and Translational Medicine, Azienda Ospedaliera Sant'Andrea, Sapienza University of Rome, Rome, Italy.
Aleksejs ZolovkinsDepartment of Interventional Radiology, Sant'Andrea Hospital, University La Sapienza, Rome, 00189, Italy.
Edoardo RonconiDepartment of Interventional Radiology, Sant'Andrea Hospital, University La Sapienza, Rome, 00189, Italy.
Michele RossiDepartment of Surgical and Medical Sciences and Translational Medicine, Azienda Ospedaliera Sant'Andrea, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Uterine fibroids (UF) affect up to 70-80% of women by age 50 and are associated with heavy menstrual bleedings, pelvic discomfort, and reduced quality of life. Uterine artery embolization (UAE) is a minimally invasive procedure that aims to reduce fibroid-related symptoms and improve patients' quality of life. Materials and methods: A prospective single-center study was conducted on 40 women who underwent UAE between November 2018 and June 2023. Primary outcomes were evaluated using the Uterine Fibroid Symptom and Quality-of-Life (UFS-QoL) questionnaire to assess symptom severity and health-related quality-of-life scores. Secondary outcomes include pain intensity, complications, requirement of additional treatments, and duration of symptoms after discharge. Results: Thirty-three patients completed the follow-up UFS-QoL questionnaire. The mean age and the mean follow-up time were 47 years (SD 14 years) and 10 months (SD 4 months), respectively. Substantial improvements were observed within all domains of the UFS-QoL questionnaire ( Discussion and conclusion: UAE offers substantial benefits for symptomatic fibroids, significantly improving HRQoL, symptom severity and pelvic pain scores, making it a valuable alternative to surgery. Complications were minor and short-lived, and the majority of patients were satisfied with the results, with no need for additional treatments. Further research is warranted to generate peri-procedural pain management consensus guidelines, clinical outcomes of radial access, and fertility-related outcomes.

Indexed as

quality of lifesymptom severityuterine artery embolizationuterine fibroid

Identifiers

PMID40823181
PMCPMC12355358

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.