Evidence map›Paper›PMID 40822966›Full record

ArticleFrontiers for young minds2025

Brain Cells that Control When We Feel Hungry.

Sarah Sarsfield, Yasmin Padovan-Hernandez, Yeka Aponte

Abstract read
In one paragraph

Article in Frontiers for young minds, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarah SarsfieldNeuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD, U.S.A.
Yasmin Padovan-HernandezNeuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD, U.S.A.
Yeka AponteNeuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD, U.S.A.

Funding

Hypothalamic neuronal circuits controlling survival behaviorsZIADA000595 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI APONTE, YEKA · 2013 to 2025
$21.3M
Intramural NIH HHS ZIA DA000595
6 · The paper itself

Abstract

As humans, we can use words like "hungry" and "full" to communicate when we need to eat throughout the day. However, mice, which are commonly used to study feeding behaviors in the laboratory, cannot tell us what they are feeling. We trained mice to tell us whether they were hungry or full. Then, we turned on and turned off certain cells in a brain region called the hypothalamus to see if these specific cell types could make a mouse feel hungry or full. Our research showed that turning on specific brain cells in a region called the arcuate nucleus of the hypothalamus caused mice to report they were hungry, even if they had just eaten and their stomachs should feel full. These results give us clues about how the brain works to control hunger.

Indexed as

brainFeedinghungerhypothalamus

Identifiers

PMID40822966
PMCPMC12356353

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.