ArticleFrontiers in endocrinology2025
Case Report: Whining toddler: could it be a serious illness.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Children in the developing stages whine for a variety of reasons. It can serve as a way of communicating when they cannot express their needs or feelings verbally. They may whine to seek attention or to deal with discomfort and frustration, especially when they want something but aren't getting it quickly enough. Additionally, it can be a response to unfamiliar stress, lack of sleep, uncomfortable environment, conflicts with siblings, or separation anxiety. Whining is common in children, usually peaking in toddlers and preschoolers. Depending on how parents respond to the behavior, some children may continue to whine beyond this age. Whining can also occur in elderly patients, especially those with dementia, and may be triggered by physical pain, hunger, psychological distress, or overstimulation in their environment. Whining is usually considered a form of behavior and not a sign of illness. Ignoring it is one option recommended for dealing with it, but rarely, it could be made to signal danger, fear, pain, or some significant underlying illness. However, persistent, unexplained whining shouldn't be simply ignored. We present a case of Type 1 diabetes mellitus with diabetic ketoacidosis (DKA), where the primary symptom was whining in a toddler who required multiple visits to the clinic and emergency department before a diagnosis was made. Whining was not initially recognized as a severe indicator of illness in this patient. To our knowledge, this is the first reported instance of newly diagnosed Type 1 diabetes mellitus with DKA in a child whose main complaint was whining.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.