Evidence map›Paper›PMID 40822894›Full record

ArticleInternational journal of general medicine2025

The Role of

Rihong Bin, Xinsheng Zheng, Ju Luo, Zhijie Liu, Haiyan Zhong, Feike Yang

Abstract read
In one paragraph

Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rihong BinDepartment of First-Aid Center, Zhuzhou Central Hospital, Zhuzhou, Hunan, 412000, People's Republic of China.ORCID 0009-0005-8506-615X
Xinsheng ZhengDepartment of First-Aid Center, Zhuzhou Central Hospital, Zhuzhou, Hunan, 412000, People's Republic of China.
Ju LuoDepartment of Geriatric Medicine, Changsha Central Hospital, Changsha, Hunan, 410000, People's Republic of China.ORCID 0000-0002-5595-9513
Zhijie LiuDepartment of Geriatric Medicine, Changsha Central Hospital, Changsha, Hunan, 410000, People's Republic of China.
Haiyan ZhongDepartment of Geriatric Medicine, Changsha Central Hospital, Changsha, Hunan, 410000, People's Republic of China.
Feike YangDepartment of Geriatric Medicine, Changsha Central Hospital, Changsha, Hunan, 410000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To identify the hub genes involved in sarcopenia and analyze their correlation with lipid metabolism. Methods: Differentially expressed genes (DEGs) from sarcopenia/non-sarcopenia cohorts in Results: Twenty key genes were identified through differential expression and diabetes-related gene screening. Functional enrichment analysis revealed their involvement in external stimulus response, inflammatory regulation, extracellular processes, adenosine monophosphate-activated protein kinase (AMPK) signaling pathway, and insulin signaling pathways (p<0.05). Adiponectin ( Conclusion: The present study confirms that glycolipid metabolism is a risk factor for sarcopenia. Both ADIPOQ and AMPK are overexpressed in sarcopenia and demonstrate a significant positive correlation. This study hypothesizes that

Indexed as

adenosine 5’-monophosphate-activated protein kinaseadiponectinglycolipid metabolismlipid metabolismsarcopenia

Identifiers

PMID40822894
PMCPMC12357585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.