ReviewInternational journal of general medicine2025
Advances in Intermittent Fasting Applications for Critically Ill Patients.
Review in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enteral nutrition remains the standard approach for nutritional support in critically ill patients, with established benefits for immune function and recovery. Intermittent fasting, a dietary strategy characterized by extended fasting intervals, has emerged as a potential adjunctive therapy. IF may induce beneficial metabolic responses such as autophagy activation and ketogenesis, contributing to improved glucose regulation, reduced intestinal permeability, modulation of gut microbiota, enhanced insulin sensitivity, and preservation of muscle mass. Unlike prolonged fasting, IF elicits these effects without causing sustained caloric deprivation. This review summarizes the current evidence regarding the physiological mechanisms, implementation strategies, clinical outcomes, and safety considerations of IF in the intensive care setting to provide a theoretical basis for further validation of the safety efficacy of the intermittent fasting paradigm for use in the ICU.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.