Evidence map›Paper›PMID 40822887›Full record

ArticlePRX life2024

Signatures of structural disorder in the developing

Christian Cupo, Cole Allan, Vikram Ailiani, Karen E Kasza

Abstract read
In one paragraph

Article in PRX life, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Christian CupoDepartment of Mechanical Engineering, Columbia University, New York, New York, 10027, USA.
Cole AllanDepartment of Mechanical Engineering, Columbia University, New York, New York, 10027, USA.
Vikram AilianiDepartment of Mechanical Engineering, Columbia University, New York, New York, 10027, USA.
Karen E KaszaDepartment of Mechanical Engineering, Columbia University, New York, New York, 10027, USA.

Funding

Mechanisms coordinating cell behaviors within tissues during developmentR35GM138380 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Karen Kasza · 2020 to 2026
$2.8M
Understanding and Controlling the Cellular Forces that Coordinate Epithelial Tissue MorphogenesisF31HD105405 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI CUPO, CHRISTIAN MICHAEL · 2021 to 2024
$189k
NICHD NIH HHS F31 HD105405NIGMS NIH HHS R35 GM138380
6 · The paper itself

Abstract

Epithelial cells generate functional tissues in developing embryos through collective movements and shape changes. In some morphogenetic events, a tissue dramatically reorganizes its internal structure - often generating high degrees of structural disorder - to accomplish changes in tissue shape. However, the origins of structural disorder in epithelia and what roles it might play in morphogenesis are poorly understood. We study this question in the

Identifiers

PMID40822887
PMCPMC12356154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.