SynthesisFrontiers in cellular neuroscience2025
Global research status, hotspots and prospects of ferroptosis in glioma: a scientometric analysis.
Synthesis in Frontiers in cellular neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The primary approach to the treatment of glioma involves surgical intervention, which is often complemented by radiotherapy, chemotherapy, and electric field therapy. Nevertheless, the prognosis for many patients remains poor. There exists an urgent necessity to identify novel replacement therapy strategies. A great breakthrough has been made in the study of ferroptosis in gliomas. The objective of this study is to conduct a systematic review of the current research status of ferroptosis in gliomas utilizing bibliometric analysis. Method: Publications related to glioma and ferroptosis from 2014 to 2025 were retrieved from the Science Core Collection (WoSCC) database. A bibliometric analysis was conducted using VOSviewer, CiteSpace, and the R package. Results: A total of 440 publications from 38 countries, with China leading the way, were included in the analysis. The number of publications related to ferroptosis in gliomas has been steadily increasing each year. The primary research institutions contributing to this field include Central South University, Nanjing Medical University, Shandong University, and Southern Medical University. Frontiers in Oncology is the leading journal for ferroptosis research in gliomas, while Cell is the most frequently cited journal in this field. These publications were authored by 2,921 individuals. Among them, Lu Shan, Wang Xuanzhong, Chen Qianxue, Sun Qian, and Xu Yang contributed the highest number of articles, while Dixon, SJ was the most frequently co-cited author. Studying the mechanisms, targets, and immunotherapy of ferroptosis in gliomas are major topics in this field. "Oxidative stress," "gpx4," and "autophagy" are popular keywords in recent years. In addition, "chemotherapy" and "miRNA" are emerging topics in this field that are closely related to this study and warrant greater attention. Conclusion: This is the first bibliometric analysis of the relationship between ferroptosis and glioma conducted over the past 11 years. The analyzed studies elucidate the regulatory mechanisms of ferroptosis and its implications in cancer cells, identify emerging research hotspots and Frontiers in recent years, and offer valuable references for scholars investigating ferroptosis in glioma, thereby facilitating the exploration of novel alternative treatment options.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.