Evidence map›Paper›PMID 40822838›Full record

ArticleBioinformation2025

Effects of dexmedetomidine and magnesium sulphate on controlled hypotension in FES surgeries.

Rajni Thakur, Shashi Kumari, Kirti Ahirwal, Sivasamy S

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rajni ThakurDepartment of Anaesthesia, Gandhi medical College, Bhopal, Madhya Pradesh, India.
Shashi KumariDepartment of Anaesthesia, Gandhi medical College, Bhopal, Madhya Pradesh, India.
Kirti AhirwalDepartment of Anaesthesia, Gandhi medical College, Bhopal, Madhya Pradesh, India.
Sivasamy SDepartment of Anaesthesia, Gandhi medical College, Bhopal, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhinosinusitis often requires functional endoscopic sinus surgery (FESS) when medical management fails, and controlled hypotension minimizes blood loss and optimizes surgical conditions. Dexmedetomidine and magnesium sulphate are commonly used to achieve controlled hypotension. Therefore, it is of interest to compare their efficacy in FESS, randomizing 60 patients to receive either dexmedetomidine or magnesium sulphate. Intraoperative mean arterial pressure (MAP) was consistently lower in the dexmedetomidine group compared to the magnesium sulphate group (p<0.01). We show that dexmedetomidine demonstrated superior performance for controlled hypotension during FESS, potentially improving surgical conditions and patient outcomes.

Indexed as

controlled hypotensionDexmedetomidineendoscopic sinus surgeryfunctional endoscopic sinus surgery (FESS)magnesium sulphate

Identifiers

PMID40822838
PMCPMC12357738

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.