ArticleBioinformation2025
Effect of resin infiltration system and pit-fissure sealant on white spot lesion: An
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Methodological Heterogeneity in Profilometric Assessment of Experimentally Demineralized Enamel as a Model of White Spot Lesions: A Systematic Review.Journal of functional biomaterials · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Demineralization causes dissolution of calcium hydroxyapatite crystals from enamel surface and leads to formation of micro-porosities resulting in chalky white patches on tooth surface thereby causing a white spot lesions. Therefore, it is of interest to compare the surface roughness, micro-hardness and masking effect of commonly used pit and fissure sealant (GC, fuji VII, IVOCLAR, helioseal F) and DMG ICON in artificial carious lesions. A total of 80 freshly extracted premolars were collected for the study. The enamel surfaces were treated using both resin infiltration and fissure sealant techniques (GC, fuji VII, IVOCLAR, helioseal F). Surface roughness was assessed with a surface profilometer, while microhardness was evaluated using the Vickers hardness test. The masking effect was determined through the Visual Analogue Scale (VAS). The highest surface roughness was observed in specimens treated with DMG ICON, followed by those treated with GC Fuji VII, while the lowest roughness was recorded by Helioseal-F in the group. In terms of microhardness, GC Fuji VII demonstrated the highest values, followed by Helioseal-F, with ICON showing the lowest. The masking ability was found to be most effective in the ICON group, which outperformed both Helioseal-F and GC Fuji VII. ICON camouflages the white spot lesions by matching the refractive index of healthy enamel. GC fuji VII helps to prevent white spot lesions by releasing fluoride, but cannot reverse or mask existing one.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.