Hemodynamic stability with clonidine versus adrenaline in mandibular third molar surgeries.

Jyoti Bhavani Penumarti, Vinay Kharsan, Abhishek Balani, Abhishek Karan, Swati Sahu

Abstract read

In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jyoti Bhavani PenumartiDepartment of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.

Vinay KharsanDepartment of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.

Abhishek BalaniDepartment of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.

Abhishek KaranDepartment of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.

Swati SahuDepartment of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This randomized clinical trial compares 2% lignocaine with clonidine versus 2% lignocaine with adrenaline for impacted mandibular third molar surgery. Hence, 70 patients aged 18-40 were randomly allocated to either group. We evaluated hemodynamic stability, onset and duration of anesthesia. Clonidine showed lower intraoperative and postoperative systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and mean arterial pressure (MAP). Though onset was slightly slower with clonidine, hemodynamic control was superior. Clonidine appears to be a safer alternative for patients requiring cardiovascular stability.

Indexed as

Clonidinelocal anesthesiathird molar surgery

Identifiers

PMID40822768

DOI10.6026/973206300211046

PMCPMC12357684

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.