Evidence map›Paper›PMID 40822758›Full record

ArticleBioinformation2025

Comprehensive genomic assessment of available probiotics in India: A framework for safety and functionality evaluation.

Swati Shrivastava, Nidhi Sharma, Abhishek Sharma, Shubhi Gupta

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Swati ShrivastavaDepartment of Biochemistry, Government Medical College, Datia, Madhya Pradesh, India.
Nidhi SharmaDepartment of Microbiology, Government Medical College, Datia, Madhya Pradesh, India.
Abhishek SharmaDepartment of Biochemistry, Government Medical College, Datia, Madhya Pradesh, India.
Shubhi GuptaDepartment of Biochemistry, Government Medical College, Datia, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic strains, defined as live microorganisms that confer health benefits to the host when administered in adequate amounts, are widely incorporated into commercial products. Therefore, assessing the safety and functional attributes of 20 commercially available probiotic strains using complete genome sequencing is of immediate importance. Our analysis revealed that 15% of the products were mislabeled, containing species different from those declared on the label. Further, 12% of the tested strains harbored transferable antimicrobial resistance genes. However, 8% Bacillus species contained virulence-associated genes. Nonetheless probiotic-related genes linked to acid and bile tolerance were consistently found in Lactobacillus strains. These findings underscore the urgent need for standardized genomic safety assessments prior to the market approval of probiotic products.

Indexed as

antimicrobial resistancefunctional propertiesgenomic analysisProbioticssafety assessmentwhole genome sequencing

Identifiers

PMID40822758
PMCPMC12357653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.