Evidence map›Paper›PMID 40822733›Full record

ArticleBMC digital health2025

A Mobile Health Intervention in Caregivers of Patients Undergoing Hematopoietic Cell Transplantation: A Randomized Controlled Trial to Examine Health-Related Quality of Life.

Xiao Cao, Michelle Rozwadowski, Thomas M Braun, Noelle E Carlozzi, Afton L Hassett, Amanda K Johnson, Evan Shereck, David A Hanauer, Sung Won Choi

Registry-linked trialAbstract read
In one paragraph

Article in BMC digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04094844 (A Randomized Trial of Roadmap 2.0), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04094844 nacompletednot on this map

A Randomized Trial of Roadmap 2.0

TypeinterventionalSponsorUniversity of Michigan Rogel Cancer CenterRan2020 to 2024Enrolled372ConditionsHematologic DiseasesArmsWearable activity sensor, Roadmap 2.0 information system, Survey administration, Roadmap 2.0 information system with Positive Activities
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiao CaoDepartment of Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Michelle RozwadowskiDepartment of Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Thomas M BraunDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Noelle E CarlozziDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Afton L HassettDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Amanda K JohnsonDepartment of Pediatrics, University of Utah, Salt Lake City, UT, USA.
Evan ShereckDepartment of Pediatrics, Oregon Health & Science University, Portland, OR, USA.
David A HanauerDepartment of Learning Health Sciences, University of Michigan, Ann Arbor, MI, USA.
Sung Won ChoiDepartment of Pediatrics, University of Michigan, Ann Arbor, MI, USA.

Funding

Training Program in Molecular HematologyT32HL007622 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SUNG WON CHOI, Jordan A. Shavit · 1986 to 2026
$9.2M
Roadmap 2.0: A randomized controlled trial using a technology-mediated platform in family caregivers of BMT patientsR01HL146354 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHOI, SUNG WON · 2019 to 2023
$1.8M
Patient-Oriented Research and Mentoring in Hematopoietic Cell TransplantationK24HL156896 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SUNG WON CHOI · 2021 to 2026
$870k
NHLBI NIH HHS K24 HL156896NHLBI NIH HHS R01 HL146354NHLBI NIH HHS T32 HL007622
6 · The paper itself

Abstract

Background: Caregivers are essential in supporting cancer patients, especially those undergoing hematopoietic cell transplantation (HCT). While traditional interventions have been beneficial for improving health-related quality of life (HRQOL), they typically require significant time and staff resources. To address this, we developed the Roadmap mHealth app, which incorporates resilience-building features based on positive psychology. The app integrates Fitbit Results: From September 08, 2020 to July 31, 2023, 168 dyads enrolled in the Roadmap study (82 intervention, 87 control). At day-120 post-HCT, there were no significant differences in PROMIS Conclusions: While the primary outcome, PROMIS Trial Registration: ClinicalTrials.gov: NCT04094844, Registered 09-16-2019.

Indexed as

digital technologiesfamily caregivershealth-related quality of life (HRQOL)hematopoietic cell transplantation (HCT)mobile health (mHealth)positive psychology

Identifiers

PMID40822733
PMCPMC12356276

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.