Evidence map›Paper›PMID 40822693›Full record

ArticleFrontiers in pediatrics2025

Case Report: A complicated case of neonatal refeeding syndrome following intrauterine growth restriction corrected by high dose thiamine supplementation.

Yixiang Wu, Hongxun Xu, Lizhong Du, Zhongyue Li

Abstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yixiang WuDepartment of Pediatric, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
Hongxun XuDepartment of Pediatric, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
Lizhong DuDepartment of Pediatric, Children's Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Zhongyue LiDepartment of Pediatric, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Refeeding syndrome (RS), marked by severe electrolyte imbalances (e.g., hypophosphatemia, hypokalemia) and thiamine deficiency, poses significant risks during nutritional rehabilitation in intrauterine growth restriction (IUGR) neonates. This case report highlights the efficacy of high-dose thiamine (2 mg/kg IV) in resolving refractory RS in a preterm IUGR infant (34 weeks, 1,415 g) unresponsive to standard electrolyte correction. Despite gradual caloric reintroduction and parenteral supplementation, the infant exhibited persistent hypophosphatemia (3.0 mmol/kg/day IV requirement), hypokalemia (4.3 mmol/kg/day IV requirement), and thrombocytopenia (nadir 27 × 10

Indexed as

case reportelectrolyte imbalanceintrauterine growth restrictionrefeeding syndromethiamine

Identifiers

PMID40822693
PMCPMC12350243

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.