Evidence map›Paper›PMID 40822588›Full record

ReviewFrontiers in cellular and infection microbiology2025

The strategies and mechanisms of enteroviruses to evade innate immunity and the vaccine progress of enteroviruses.

Yangqi Yin, Xuyang Chi, Yandong Feng, Qinglian Jiang

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yangqi Yin *Department of Pediatrics, General Hospital of Fushun Mining Bureau of Liaoning Health Industry Group, Fushun, Liaoning, China.
Xuyang Chi *Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Yandong FengDepartment of Pediatrics, The First Hospital of Lanzhou University, Lanzhou, China.
Qinglian JiangDepartment of General Pediatrics, Zhongshan City People's Hospital, Zhongshan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses (EVs) are a group of highly contagious RNA viruses that can cause a wide range of diseases, from mild infections to severe complications like neurological disorders and myocarditis. This review focuses on the innate immune evasion strategies employed by EVs, highlighting their mechanisms and consequences. EVs evade host immune responses through various tactics, including inhibiting pathogen recognition receptors (PRRs) such as toll-like receptors (TLRs) and RIG-I-like receptors (RLRs), disrupting key signaling pathways like nuclear factor kappa-B (NF-κB) and (JAK)-signal transducers and activators of transcription (STAT), and directly targeting interferon (IFN) signaling components. Specific viral proteases, such as 2A protease (2A

Indexed as

EnterovirusEnterovirus InfectionsHost-Pathogen InteractionsImmune EvasionImmunity, InnateViral VaccinesAnimalsHumansSignal TransductionToll-Like ReceptorsViral ProteinsToll-Like ReceptorsViral ProteinsViral Vaccinesenterovirusimmune evasion strategiesinnate immune responseinterferonvaccine

Identifiers

PMID40822588
PMCPMC12350268

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.