Evidence map›Paper›PMID 40822580›Full record

ArticleFrontiers in cellular and infection microbiology2025

Hui-Ying Liu, Yao Li, Yi-Lu Lin, Yu-Jia Tang, Jin-Da Zhao, Jia Xu, Kuo Wang, Ying-Fei Zhi, Yan Zhang, Jia-Le Deng and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Journal of microbiology and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hui-Ying Liu *Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Yao Li *Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Yi-Lu Lin *Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Yu-Jia Tang *Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Jin-Da ZhaoDepartment of Critical Care Medicine, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China.
Jia XuDepartment of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Kuo WangDepartment of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Ying-Fei ZhiDepartment of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Yan ZhangDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Jia-Le DengDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Kai KangDepartment of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Ying ChenDepartment of Critical Care Medicine, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China.
Yang GaoDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sepsis is one of the leading causes of mortality among intensive care unit (ICU) patients. The intestinal tract is the primary organ affected by sepsis, resulting in dysbiosis of the gut microbiota and negatively impacting long-term prognosis. This study investigated the protective effects of Methods: Distilled water was administered orally by intragastric for 4 weeks in control group and sepsis group. Results: Sepsis led to an increase in the expression of IL-6, TNF-α, and a decrease in the expression of occludin. After treatment with Conclusion: Sepsis induces impairment of intestinal barrier function and exacerbates inflammatory responses. The use of

Indexed as

Gastrointestinal MicrobiomeIntestinal DiseasesSaccharomyces boulardiiSepsisAnimalsIntestinal Barrier FunctionRatsRats, Wistar16S rRNA gene sequencinggut barrier dysfunctiongut microbiotaSaccharomyces boulardiisepsis

Identifiers

PMID40822580
PMCPMC12350329

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.