Evidence map›Paper›PMID 40822579›Full record

ArticleFrontiers in cellular and infection microbiology2025

Meropenem/vaborbactam activity against carbapenem-resistant

Francesca Sivori, Massimo Francalancia, Mauro Truglio, Ilaria Cavallo, Carmelina Pronesti, Giorgia Fabrizio, Ilaria Celesti, Andrea Cazzani, Lorenzo Furzi, Fulvia Pimpinelli and 1 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Targeting KPC-ProducingMicroorganisms · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesca Sivori *Microbiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Massimo Francalancia *Microbiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Mauro TruglioMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Ilaria CavalloMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Carmelina PronestiHospital Infection Control Committee, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy.
Giorgia FabrizioDepartment of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, Rome, Italy.
Ilaria CelestiMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Andrea CazzaniMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Lorenzo FurziMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Fulvia PimpinelliMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Enea Gino Di DomenicoMicrobiology and Virology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Carbapenem-resistant Methods: This study investigated the Results: Whole-genome sequencing identified the isolates as ST101 and ST307, harboring resistance determinants including Discussion: These findings demonstrate that MEV exhibits activity against planktonic and biofilm-associated CRKP cells and highlight the need for further investigation in managing catheter-related bloodstream infections caused by multidrug-resistant

Indexed as

Anti-Bacterial AgentsBacteremiaBoronic AcidsCarbapenem-Resistant EnterobacteriaceaeCatheter-Related InfectionsKlebsiella InfectionsKlebsiella pneumoniaeMeropenemAnimalsBiofilmsCarbapenemsDisease Models, AnimalDrug CombinationsDrug Resistance, Multiple, BacterialHeterocyclic Compounds, 1-RingHumansAnti-Bacterial AgentsBoronic AcidsCarbapenemsDrug CombinationsHeterocyclic Compounds, 1-RingMeropenemmeropenem and vaborbactamvaborbactambiofilm-associated infectionscarbapenem-resistant Klebsiella pneumoniaecatheter-related bloodstream infectionsmeropenem/vaborbactammultidrug-resistant plasmidsurgical site infection

Identifiers

PMID40822579
PMCPMC12350291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.