ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2025
Assessment of retinal blood flow changes in early Parkinson's disease: An optical coherence tomography angiography study.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors.
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Abstract
Background: To evaluate retinal microvasculature and choroidal thickness in patients with Parkinson's disease (PD) with optical coherence tomography angiography (OCTA). Materials and Methods: Forty-one eyes from 41 patients diagnosed with PD and 41 eyes of 41 healthy subjects underwent retinal and choroidal assessment using swept source DRI Triton OCT (Topcon, Tokyo, Japan). Macular perfusion parameters, including superficial and deep foveal avascular zones (FAZs and FAZd, respectively), superficial capillary plexus (vascular density [VDs]), deep capillary plexus (VDd), and choriocapillaris (VDc), were compared with healthy controls. Results: The central sectors of the VDs, VDd, and VDc measurements ( Conclusion: PD seems to affect macular and choroidal microcirculation. The reduced choroidal thickness and increased central sectors of the VDs, VDd, and VDc measurements may provide disease activity information. However, more comprehensive studies on OCTA demonstrating clinical utility in PD are needed to support our findings.
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