ArticleOTA international : the open access journal of orthopaedic trauma2025
Osseous union after antibiotic cement application with retention of stable orthopaedic hardware in fracture-related infections without union.
Article in OTA international : the open access journal of orthopaedic trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate treatment outcomes of patients treated with antibiotic impregnated cement applied over implanted orthopaedic hardware, in the setting of fracture-related infection, without osseous union, after open reduction internal fixation. Design: Retrospective observational case series. Setting: Level 1 trauma center. Patients/Participants: Retrospective review of 15 patients who underwent antibiotic cement application to their retained plate for the treatment of acute fracture-related infections (12) and acutely infected nonunion (3) status after open reduction internal fixation (ORIF). Outcomes: Suppression of infection and radiographic union by final follow-up. Results: Antibiotic plate application successfully led to fracture union in all 15 patients (100%). Three of these patients (20%) required removal of hardware. Of these 3 patients, all 3 achieved fracture union before hardware removal. However, 2 of these patients developed a chronic infection and were placed on long term PO antibiotics for chronic infection suppression, thus making them ineligible for classification as free of infection. Conclusions: The results of this study suggest that application of antibiotic cement to retained plates/screws for ORIF during treatment of both acute fracture infections and acutely infected nonunions is a viable technique to achieve osseous union. Hardware removal may be required in some cases. Use of this technique supports fracture healing and local infection control, while maintaining construct stability long enough to achieve fracture union.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.