Evidence map›Paper›PMID 40822461›Full record

SynthesisFrontiers in pharmacology2025

Comparison of the analgesic effects of ultrasound-guided erector spinae plane block and quadratus lumborum block: a systematic review and meta-analysis.

Lin Wu, Weiyi Zhang, Yiyong Wei, Donghang Zhang

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07346417 (Erector Spinae Plane Block Versus Quadratus Lumborum Block for Post Operative Analgesia in Pediatric Kidney Surgery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07346417 nanot yet recruitingnot on this map

Erector Spinae Plane Block Versus Quadratus Lumborum Block for Post Operative Analgesia in Pediatric Kidney Surgery

TypeinterventionalSponsorAssiut UniversityRan2025 to 2028Enrolled100ConditionsKidney DiseasesArmsQuadratus lumborum block teqnique, Erector spinae plane block Technique
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lin Wu *Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Weiyi Zhang *Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Yiyong WeiDepartment of Anesthesiology, Longgang Maternity and Child Institute of Shantou University Medical College (Longgang District Maternity and Child Healthcare Hospital of Shenzhen City), Shenzhen, China.
Donghang ZhangDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Erector spinae plane block (ESPB) and quadratus lumborum block (QLB) are commonly used for perioperative analgesia in various surgeries. An increasing number of randomized controlled trials (RCTs) have compared the analgesic effect and safety of ESPB with those of QLB, but the conclusions are controversial. This study was designed to identify whether ultrasound-guided ESPB was better than the QLB for postoperative analgesia. Methods: To identify RCTs comparing ESPB with QLB for postoperative analgesia, we searched PubMed, Embase, the Cochrane Library, and Web of Science. The primary outcome was postoperative analgesic consumption over 24 h. The secondary outcomes included the time to the first analgesic request, postoperative resting pain scores, block performance time, postoperative rescue analgesia rate, incidence of complications, and postoperative satisfaction. RevMan 5.4 software was used in the analysis. Subgroup analysis and sensitivity analysis were performed to explore the source of heterogeneity and test the reliability of the pooled results. The quality of evidence was systematically assessed via the GRADE evaluation. Results: Twenty-seven studies involving 1942 patients were included. Compared with QLB, ESPB consumed fewer 24-h postoperative analgesics (WMD, -4.03; 95% CI, -6.25 to -1.82; Conclusion: Moderate-to high-quality evidence indicates that ESPB is superior to QLB for postoperative analgesia because of less postoperative analgesic consumption, faster block performance and a lower incidence of postoperative nausea and vomiting. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024607988.

Indexed as

analgesiaerector spinae plane blockmeta-analysispostoperative painquadratus lumborum blocksystematic review

Identifiers

PMID40822461
PMCPMC12355214

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.