Evidence map›Paper›PMID 40822448›Full record

ArticleTransboundary and emerging diseases2025

Effect of Hydroxychloroquine in a Mouse Model of Abortion Caused by

Haoran Liu, Zhirong Yan, Jingyu Wang, Xiaofeng Liu, Weiyu Zhang, Jun Liu, Qisheng Peng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Analysis of factors affecting fibrosis reversal in patients with metabolic associated steatohepatitis based on magnetic resonance elastography].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haoran LiuState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0009-0005-1172-5458
Zhirong YanState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0009-0009-9479-4246
Jingyu WangState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0009-0009-9238-039X
Xiaofeng LiuClinical Laboratory, Tumor Hospital of Jilin Province, Changchun, Jilin, China.ORCID https://orcid.org/0000-0003-3487-5510
Weiyu ZhangJilin Provincial Center for Disease Control and Prevention, Institute of Microbiology Department, Changchun, Jilin, China.ORCID https://orcid.org/0009-0005-4070-2378
Jun LiuChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, Jilin, China.ORCID https://orcid.org/0000-0001-6597-586X
Qisheng PengState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-6971-6774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxychloroquine (HCQ) has showed beneficial effects on pregnancy outcomes in systemic erythaematosus lupus (SLE) by its anti-inflammatory and immunomodulatory properties. However, the role of HCQ in preventing abortion caused by infectious diseases remains unknown. In this study, we choose

Indexed as

Brucella abortusBrucellosisHydroxychloroquineAnimalsDisease Models, AnimalFemaleMiceMice, Inbred BALB CPregnancyHydroxychloroquineabortionBrucellahydroxychloroquineinflammationtype IV secretion system

Identifiers

PMID40822448
PMCPMC12356681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.