Evidence map›Paper›PMID 40822389›Full record

ArticleFrontiers in microbiology2025

The encoded and expressed biosynthetic potential of Greenland Ice Sheet microbes.

Ate H Jaarsma, Katie Sipes, Athanasios Zervas, Helen K Feord, Francisco Campuzano Jiménez, Mariane S Thøgersen, Liane G Benning, Martyn Tranter, Alexandre M Anesio

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ate H JaarsmaDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Katie SipesDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Athanasios ZervasDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Helen K FeordGFZ Helmholtz Centre for Geosciences, Potsdam, Germany.
Francisco Campuzano JiménezDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Mariane S ThøgersenDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Liane G BenningGFZ Helmholtz Centre for Geosciences, Potsdam, Germany.
Martyn TranterDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Alexandre M AnesioDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supraglacial habitats of the Greenland Ice Sheet (GrIS) harbor active microbial communities. Microbes produce a plethora of natural products, which hold great promise in biotechnology. Understudied environments such as the Greenland Ice Sheet are therefore of interest for the discovery of unknown biosynthetic gene clusters (BGCs) that encode these compounds. Though many applications of these natural products have been identified, little is known about their ecological function for the producer itself. Some hints exist toward roles in competition and environmental adaptation, yet confirmation of the expression of these BGCs in the natural environment is often lacking. Here, we investigated the expression of BGCs in supraglacial habitats of the GrIS. Using total RNA sequencing, we conducted a seasonal study to analyze metatranscriptomes of ice and cryoconite habitats over a 21-day period during the ablation season. Genome mining on metagenomic contigs identified BGCs within ice and cryoconite metagenomes, after which the metatranscriptomes were mapped to them. Our study identified a majority of previously unknown BGCs, 59% of which are actively expressed

Indexed as

biosynthetic gene clusters (BGCs)Greenland Ice Sheetmetatranscriptomicsmicrobial community ecologysupraglacial habitats

Identifiers

PMID40822389
PMCPMC12350317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.