Evidence map›Paper›PMID 40822367›Full record

ReviewMethodist DeBakey cardiovascular journal2025

Cardiovascular Health During Menopause Transition: The Role of Traditional and Nontraditional Risk Factors.

Samuel Yousefzai, Zahir Amin, Huzaifa Faizan, Maheen Ali, Suha Soni, Michael Friedman, Abeera Kazmi, Faith Elise Metlock, Garima Sharma, Zulqarnain Javed

Abstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Samuel YousefzaiIndependent Researcher, US.ORCID https://orcid.org/0009-0004-7473-0943
Zahir AminThe University of Texas Medical Branch at Galveston, University of Houston, Houston, Tesxas, US.ORCID https://orcid.org/0000-0002-9135-0254
Huzaifa FaizanWilliam Carey College of Osteopathic Medicine, Hattiesburg, Mississippi, US.ORCID https://orcid.org/0009-0006-6415-2996
Maheen AliUniversity of Houston, Houston, Texas, US.ORCID https://orcid.org/0009-0005-5635-9412
Suha SoniThe University of Texas Health, San Antonio, San Antonio, Texas, US.ORCID https://orcid.org/0000-0002-0795-8700
Michael FriedmanGeorge Washington University School of Medicine, Washington, DC, US.ORCID https://orcid.org/0009-0001-9341-7571
Abeera KazmiShifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.ORCID https://orcid.org/0009-0007-6744-9901
Faith Elise MetlockInova Health System, Falls Church, Virginia, US.ORCID https://orcid.org/0000-0001-6005-1844
Garima SharmaInova Schar Heart and Vascular, Falls Church, Virginia, US.ORCID https://orcid.org/0000-0001-7254-2077
Zulqarnain JavedHouston Methodist DeBakey Heart & Vascular Center, Center for Cardiovascular Computational Health & Precision Medicine, Houston Methodist, Houston, Texas, US.ORCID https://orcid.org/0000-0002-4137-9198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perimenopause, or menopause transition (MT), is a critical life stage that encompasses significant physiological, emotional, and psychosocial changes that impact women's cardiovascular health and quality of life. The decline in estrogen during MT induces adverse metabolic changes that increase the risk of dyslipidemia, obesity, insulin resistance, atherogenesis, and poor downstream outcomes such as diabetes, hypertension, stroke, and other adverse changes. Concurrently, stress plays an important role in shaping overall cardiovascular well-being during MT and long-term heart health post-menopause. In addition, nontraditional risk factors-particularly social determinants of health (SDoH) such as economic well-being, access to health care, built environment, social support, and others-are key upstream determinants of cardiovascular disease in women during perimenopause. Coordinated efforts are needed to screen, identify, and address the primary SDoH for optimal heart health in the clinically vulnerable MT patient population. Patient-centered care pathways that focus on assessing social needs and connecting socially vulnerable patients with available community resources are much needed for holistically addressing patient needs. Community-centered efforts are key to addressing persistent inequities in women's cardiovascular health via navigation and connection to community resources that may help address SDoH barriers.

Indexed as

Cardiovascular DiseasesMenopausePerimenopauseWomen's HealthAge FactorsFemaleHealthcare DisparitiesHealth Services AccessibilityHealth Status DisparitiesHeart Disease Risk FactorsHumansPrognosisRisk AssessmentRisk FactorsSocial Determinants of Healthcardiovascular diseasecardiovascular healthmenopause transitionperimenopause

Identifiers

PMID40822367
PMCPMC12352403

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.