Evidence map›Paper›PMID 40822346›Full record

ArticleiScience2025

Transient regulatory T cell manipulation is limited by anti-antibody responses in HIV-1 envelope immunized rhesus macaques.

Shuqin Gu, Kan Luo, Tarra A Von Holle, Thaddeus C Gurley, Hilary Bouton-Verville, Laura L Sutherland, Robert Parks, Xiaoying Shen, Rachel L Spreng, Georgia D Tomaras and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shuqin GuDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Kan LuoDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Tarra A Von HolleDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Thaddeus C GurleyDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Hilary Bouton-VervilleDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Laura L SutherlandDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Robert ParksDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Xiaoying ShenDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Rachel L SprengDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Georgia D TomarasDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
David C MontefioriDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Hua-Xin LiaoDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Barton F HaynesDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
M Anthony MoodyDuke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD25

Indexed as

Biological sciencesImmunologyVirology

Identifiers

PMID40822346
PMCPMC12355595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.