Evidence map›Paper›PMID 40822336›Full record

ArticleiScience2025

Impact of conduit-filling interactions on the efficacy of fiber and hydrogel fillers in nerve conduits.

Flavia Millesi, Sascha Mero, Sebastian Rihl, Sophie Steinwenter, Sarah Stadlmayr, Anton Borger, Paul Supper, Maximilian Haertinger, Leon Ploszczanski, Gerhard Sinn and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Flavia MillesiResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Sascha MeroResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Sebastian RihlResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Sophie SteinwenterResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Sarah StadlmayrResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Anton BorgerResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Paul SupperResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Maximilian HaertingerResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Leon PloszczanskiInstitute for Physics and Materials Science, University of Natural Resources and Life Sciences, Peter-Jordan-Straße 82, 1190 Vienna, Vienna, Austria.
Gerhard SinnInstitute for Physics and Materials Science, University of Natural Resources and Life Sciences, Peter-Jordan-Straße 82, 1190 Vienna, Vienna, Austria.
Aida NaghilouResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Lorenz SemmlerResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.
Christine RadtkeResearch Laboratory of the Department for Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nerve conduits offer an alternative to autologous nerve grafts, yet their clinical application remains restricted to short injuries with unsatisfactory outcomes. This study aimed to elucidate the factors responsible for these poor results. We systematically compared three commercially available conduits, assessing their impact on Schwann cells and fibroblasts

Indexed as

BiomaterialsMaterials scienceNeuroscience

Identifiers

PMID40822336
PMCPMC12357111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.