ArticleOpen forum infectious diseases2025
Lack of Association Between
Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Fungal diagnostic stewardship in immunocompromised populations: a focus on molds and dimorphic fungi.Clinical microbiology reviews · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Methods: Retrospective review of urine antigen tests and time to resolution of histoplasmosis for patients without HIV who were hospitalized between 1 January 2015 and 1 February 2024, and who had >2 sequential urine antigen tests performed. Results: Twenty-seven patients were included: 24 (89%) had disseminated infection and 23 (85%) were immunocompromised. Antigen values were followed for as long as 39 to 58 months in some patients. Changes in antigen values over time roughly fell into 3 groups. For 7 patients, the decrease in antigen corresponded with clinical response. Five patients, whose initial antigen levels were above the assay's level of quantification, had persistence at this high level for up to 15 months after clinical response. For the remaining 15 patients, antigen slowly decreased, sometimes transiently increased, not mirroring the clinical response; 4 patients had persistent antigenuria for as long as 22 to 48 months after all symptoms, signs, and laboratory abnormalities had resolved. Conclusions: These results support the concept that persistently positive
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.