Assessing the clinical relevance of MRI findings in adult achondroplasia patients with lumbar spinal stenosis.

Husule Cai, Chady Omara, Carmen L A Vleggeert-Lankamp

Abstract read

In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Surgical Correction of Thoracolumbar Kyphosis in Achondroplasia: Complications, Pitfalls, and Reflections on the Pursuit of Maximal Realignment in View of Correction Leading to Functional Disability.Journal of clinical medicine · 2026
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Husule CaiDepartment of Neurosurgery, Leiden University Medical Centre, Leiden, the Netherlands.

Chady OmaraDepartment of Neurosurgery, Leiden University Medical Centre, Leiden, the Netherlands.

Carmen L A Vleggeert-LankampDepartment of Neurosurgery, Leiden University Medical Centre, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Achondroplasia (Ach) is the most common form of dwarfism, and lumbar spinal stenosis (LSS) becomes the primary problem for adult Ach patients. Research question: This study aims to determine the cutoff values of LSS for surgical decompression. Material methods: MRIs of adult achondroplasts with symptomatic lumbar spinal stenosis referred to our Medical Centre between 2019 and 2022 were reviewed. The degree of lumbar spinal stenosis was assessed by the Schizas scale and dural sac cross-sectional area (DSCA). Regression analysis was used to evaluate the association between treatment decisions and the degree of stenosis, while receiver operating characteristic (ROC) analysis was performed to identify cutoff values. A follow-up survey was conducted to validate clinical effectiveness. Results: In total, 68 patients were included (mean age: 46.2 ± 15.4 years; 60 % female). Individuals subjected to decompression had higher Schizas scales (p < 0.001) and smaller DSCA (62.5 ± 34.3 mm Discussion and conclusion: Schizas scales C and D or DSCA smaller than 62 mm

Indexed as

AchondroplasiaDural sac cross-sectional areaLumbar decompressionLumbar spinal stenosisNeurologic claudicationSchizas scales

Identifiers

PMID40822260

DOI10.1016/j.bas.2025.104374

PMCPMC12354802

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