Evidence map›Paper›PMID 40822194›Full record

ArticleArthroscopy techniques2025

Partial-Thickness Bursal-Site Rotator Cuff Repair With Autologous Bursa Augmentation.

Marco T Di Stefano, Michael Young, Jonas Vorbau, Alexa Cohen, Stefan Minyayluk, Alireza Gholipour, Mary Beth McCarthy, Augustus D Mazzocca

Abstract read
In one paragraph

Article in Arthroscopy techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco T Di StefanoDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.
Michael YoungDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.
Jonas VorbauDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.
Alexa CohenDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.
Stefan MinyaylukDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.
Alireza GholipourDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.
Mary Beth McCarthyDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.
Augustus D MazzoccaDivision of Sports Medicine, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard School of Medicine, Massachusetts General Brigham, Boston, Massachusetts, U.S.A.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotator cuff tears are persistent problems that motivate clinicians to explore innovative solutions to enhance patient healing outcomes. Bursal cells have proliferative, differentiating, and migrating properties, making them a feasible solution to this problem. This article aims to show a possible solution for symptomatic, refractory bursal-sided rotator cuff tears using a bio-inductive scaffold (BIS) with bursa augmentation. This procedure is eligible for patients with bursal-sided rotator cuff tears that have been refractory to conservative treatment. The surgical technique consists of an augmentation of a BIS filled with minced bursal tissue, a source of mesenchymal stem cells (MSCs). The scaffold serves as a barrier to hold the bursal cells on top of the lesion, promoting cell-to-cell contact between tenocytes and MSC-rich bursal cells, thereby enhancing their full potential. This surgical technique is a straightforward, reproducible, and effective approach to enhancing rotator cuff repair. By using autologous bursal MSCs and a BIS, this technique promotes healing, potentially reducing retear rates and accelerating recovery. The use of the BIS further supports the repair, ensuring optimal tissue healing in the tendon-bone junction.

Identifiers

PMID40822194
PMCPMC12350693

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.