ReviewJournal of Alzheimer's disease reports
Bibliometric analysis of pathological mechanisms in Alzheimer's disease: Applications based on mouse models.
Review in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by memory loss and cognitive decline. Animal models play a key role in exploring its pathophysiological mechanisms. Objective: To analyze global research trends and knowledge structure in AD pathophysiological mechanisms based on animal models. Methods: Publications from 2014 to 2023 were retrieved from the Web of Science Core Collection. CiteSpace and VOSviewer were used for bibliometric analysis and data visualization. Results: A total of 2169 publications were identified, with a steady growth trend. The United States and China were the leading contributors, with Harvard University as a major collaborative hub. The Journal of Alzheimer's Disease published the most articles, while the Journal of Neuroscience had the highest co-citation frequency. Holtzman DM was a key author in the field. Nine keyword clusters were identified, including insulin resistance, amyloid beta, and oxidative stress. Emerging topics include synapse loss, gut microbiota, and NLRP3 inflammasome. Conclusions: This study provides a concise overview of global research on AD pathophysiological mechanisms in animal models, offering valuable insights for future research directions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.