Evidence map›Paper›PMID 40822026›Full record

ArticleAPL photonics2024

Mid-infrared hyperspectral microscopy with broadband 1-GHz dual frequency combs.

Peter Chang, Ragib Ishrak, Nazanin Hoghooghi, Scott Egbert, Daniel Lesko, Stephanie Swartz, Jens Biegert, Gregory B Rieker, Rohith Reddy, Scott A Diddams

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in APL photonics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peter ChangDepartment of Electrical, Computer and Energy Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, USA.ORCID 0000-0001-8713-5079
Ragib IshrakDepartment of Electrical and Computer Engineering, University of Houston, Houston, Texas 77204, USA.ORCID 0009-0008-9208-6249
Nazanin HoghooghiDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, USA.ORCID 0000-0001-9206-2003
Scott EgbertDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, USA.ORCID 0000-0002-9745-6869
Daniel LeskoDepartment of Chemistry, University of Colorado at Boulder, Boulder, Colorado 80309, USA.ORCID 0000-0002-8573-8295
Stephanie SwartzTime and Frequency Division, National Institute of Standards and Technology, Boulder, Colorado 80305, USA.ORCID 0000-0001-6252-1731
Jens BiegertICFO - Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, Castelldefels 08860, Barcelona, Spain.ORCID 0000-0002-7556-501X
Gregory B RiekerDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, USA.ORCID 0000-0003-0762-7896
Rohith ReddyDepartment of Electrical and Computer Engineering, University of Houston, Houston, Texas 77204, USA.
Scott A DiddamsDepartment of Electrical, Computer and Energy Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, USA.ORCID 0000-0002-2144-0764

Funding

Early detection of treatment response in myelofibrosis by polarization-sensitive mid-infrared spectroscopic imagingR01HL173597 · NHLBI · UNIVERSITY OF HOUSTON · PI Rohith Reddy · 2024 to 2026
$2.0M
Improving the Accuracy of Lupus Nephritis Diagnosis using Biomarkers Derived from Ultraviolet and Mid-infrared Spectroscopic ImagingR01DK135870 · NIDDK · UNIVERSITY OF HOUSTON · PI Rohith Reddy · 2024 to 2026
$1.8M
NHLBI NIH HHS R01 HL173597NIDDK NIH HHS R01 DK135870
6 · The paper itself

Abstract

Mid-infrared microscopy is an important tool for biological analyses, allowing a direct probe of molecular bonds in their low energy landscape. In addition to the label-free extraction of spectroscopic information, the application of broadband sources can provide a third dimension of chemical specificity. However, to enable widespread deployment, mid-infrared microscopy platforms need to be compact and robust while offering high speed, broad bandwidth, and high signal-to-noise ratio. In this study, we experimentally showcase the integration of a broadband, high-repetition-rate dual-comb spectrometer (DCS) in the mid-infrared range with a scanning microscope. We employ a set of 1-GHz mid-infrared frequency combs, demonstrating their capability for high-speed and broadband hyperspectral imaging of polymers and ovarian tissue. The system covers

Identifiers

PMID40822026
PMCPMC12352579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.