ReviewPeerJ2025
Sampling strategies for digestive system flora studies: current research and perspectives.
Review in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Characterization of fecal bacterial microbiomes according to fecal color, consistency, and sample type in piglets before and after weaning.Frontiers in veterinary science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The digestive system is significantly associated with the incidence and progression of various diseases. Investigating its microbial community will aid in the diagnosis, treatment, and prognostication of digestive pathologies. Microbial composition varies not only between distinct organs but also within different regions of the same organ. Additionally, dynamic shifts in microbial composition occur throughout various phases of the disease, complicating research. This study systematically evaluated the biological samples and diverse collection methods employed in digestive system microbiota research, with the aim of guiding sample selection and collection strategies for future microbial studies. Methodology: We conducted a comprehensive literature review using professional databases such as PubMed and Web of Science. The focus of this review is on microbial community research, particularly the use of high-throughput sequencing to compare different samples of the same organization, as well as the impact of different sampling methods on microbial community structure of the same sample. Results: A diverse array of microbiological samples are available for study, including saliva, endoscopic biopsies, luminal mucosa, luminal fluid, feces, bile, and surgically excised tissues. Multiple techniques exist to obtain specimens from identical locations, each with a unique set of benefits and limitations. Conclusions: When selecting specimens and sampling methods for microbiota studies, it is essential to consider the characteristics of the microbiota population, research environment, and the objectives of the study. Despite the importance of appropriate sampling for microbial community studies, consensus on the optimal sample type and collection method remains elusive.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.