ArticlePeerJ2025
The impact of changes in LH levels in flexible antagonist protocols on the clinical outcomes of fresh IVF/ICSI cycles in populations of POSEIDON groups 1 and 2: a retrospective cohort study.
Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the impact of changes in luteinizing hormone (LH) levels during ovulation induction using flexible gonadotropin-releasing hormone antagonist (GnRH-A) regimens in POSEIDON groups 1 and 2 on the clinical outcomes of fresh Method: A retrospective analysis was conducted on the clinical data of females in POSEIDON groups 1 and 2 who underwent IVF/ICSI using a flexible GnRH-A regimen at the Reproductive Medicine Center of Fujian Maternal and Child Health Hospital from January 2017 to December 2022. According to the values of change in LH [(LH level on the trigger day - baseline LH)/baseline LH] × 100%, the study subjects were divided into five groups. The general information, laboratory indicators, and clinical outcomes of each group were compared. Results: In POSEIDON group 1, a significant difference was observed in terms of the number of retrieved eggs, mature eggs, fertilization number (two pronuclei (2PN) number), and cleavage among all groups (all Conclusion: The use of a flexible GnRH-A regimen to induce ovulation in the POSEIDON groups 1 and 2 can lead to better-controlled ovarian stimulation (COS) outcomes. This involves the LH level on trigger day decreasing within the range of 0-100% from baseline (with optimal range being ≥ -100% to -50%). This trend was more obvious in the POSEIDON group 2 population.
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